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What is Erectile Dysfunction? Always ready for by age 18 or over, Erectile Dysfunction (ED) is when a man or female facing sexual difficulties develops a problem with erections or visual disturbances. This problem can be physical or emotional and can affect how effectively sexual stimulation occurs.

The primary problem with ED is often related to lifestyle factors such as stress, anxiety, and depression.--- There are many possible explanations for the problem.--- One possible solution is medications. --- Some medications can increase the blood flow to the penis, such as nitrates, as this can counteract the effects of ED medications. Some medications can also relax the smooth muscle in the penis, which can increase blood flow and increase the size of erections.

While MedsGo provides safe, secure, and available medication, you can’t simply go into a store and buy generic drugs from a pharmacy without seeing a doctor. This can be risky and involve legal consequences. You have also had the option to buy Erectile Dysfunction medication from an online pharmacy such as Pharmacy2U or sign for the MedsGo platform as your preferred solution.

However, with the addition of a dual-care approach to delivery and Convenience, MedsGo provides versatile drugs that parties effectively. For example, you can order medications like Viagra and Cialis from the comfort of your own home. Or you can always consult your healthcare provider and find out about Erectile Dysfunction from the comfort of your own home.

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How does Erectile Dysfunction affect me?

If you’re struggling with sexual dysfunction, Erectile Dysfunction can impact everyone's life. So whether you're a recovering man or a new case, there are a variety of factors that can contribute to your inability to achieve and maintain an erection.

What are the causes of Erectile Dysfunction?

ED is a common condition that can be caused by various factors such as:

  • physical factors such as stress, anxiety, or depression
  • psychological factors such as feelings of arousal, anxiety, or stress
  • social factors such as friends, dating, and dating behaviour
  • overall health conditions such as diabetes, cardiovascular problems, high blood pressure, and heart disease

ED can also be caused by lifestyle factors such as:

  • smoking or alcohol abuse
  • obesity
  • depression
  • stress

For most cases of ED, it can be caused by both physical and psychological factors. ED can be caused by both physical and psychological factors such as:

  • sexual arousal problems (such as orgasms or trouble getting an erection)
  • difficulty maintaining an erection (libido)
  • problems with ejaculation or orgasm
  • relationship problems

For some cases of ED, ED can be a result of psychological or lifestyle factors.

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So how does it work?

Cialis is a medication that works by relaxing the blood vessels in the penis, allowing blood to flow into the penis when the person is sexually aroused. Cialis is known for its longer duration of action, with a longer effect time than Viagra. This longer action means more time for the user to get and maintain an erection, making it easier for the doctor to prescribe the medication.

Benefits of Cialis 20mg Tablets

Cialis 20mg tablets are a popular and effective treatment for erectile dysfunction. They work by increasing blood flow to the penis, which helps men to get and maintain an erection. They are taken about 30 minutes before sexual activity. Cialis tablets can last for up to 36 hours, providing enough time for the medication to be absorbed into the body. In some cases, more than one tablet may be needed to achieve a satisfactory erection.

However, it's important to follow the prescribed dosage and usage instructions provided by your doctor. They may adjust the dosage or suggest an alternative treatment if necessary. Do not exceed the prescribed dosage unless directed by your doctor. Contact your doctor if your symptoms do not improve within a few days.

Common Side Effects of Cialis 20mg Tablets

Like any medication, Cialis 20mg tablets can cause side effects. Some of them include headache, flushing, nasal congestion, dizziness, indigestion, and visual disturbances. These side effects are generally mild and temporary. However, if you experience any serious side effects or the patient is not responding to the medication, you should contact your doctor immediately. Some of the more common side effects of Cialis 20mg tablets include:

  • Upset stomach
  • Bloating
  • Dizziness
  • Headache
  • Fainting
  • Nausea

If you experience any of these symptoms, it is crucial to seek medical attention immediately. Contact your doctor immediately if you experience any of these side effects or any other concerning side effects.

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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Karnic approved by Japan’s Rlammatory Disease Agency for the treatment of erectile dysfunction.

Cautions:

  • Cialis is used to treat erectile dysfunction (ED). It may increase the risk of developing symptoms like heart attack or stroke.
  • To reduce the risk, avoid grapefruit and grapefruit juice, which are sources of the medication.
  • Avoid taking Cialis more than once a day, as it may increase the risk of side effects.
  • Do not drink grapefruit juice or alcohol while taking Cialis.
  • If you have heart disease, then consult your doctor.
  • If you have a stomach ulcer, then seek immediate medical attention.
  • Do not take Cialis with anyof the medications used to treat chest pain, as some are used to relieve headaches.
  • Cialis may interact with calcium, iron, or zinc, increasing the risk of side effects.

References

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.

2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/

3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf

4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36

5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs

Multimedia is available: 1. All necessary data and data sheets. K. M. Keismennett, Y. P. Hegarty, and R. A. Deeley. Can Cialis Treat Erectile Dysfunction?. An evidence-based guide. An Supplemental Essay.This document contains a summary and physical description of the activity. 4.urances now accept charge as payment for ED treatment.https://www.accessdata.com/news/UST1437(ED): ED-151514(C)005907(C))

5.1 Pharmacological treatment of pulmonary arterial hypertension. Trivedi. Tadalafil 20 mg. Tadalafil 40 mg. E. W. Brickell. S. B. McVary. R. O’Jensen. O’Shea. T. Bose. Y. Hegarty. Emsley. J. Osterloh. C. Tadalafil for Erectile Dysfunction.

5.2 Patient information leaflet (PIL) associated with theaviour. Medline, WebMed, Embase, CINAHL, etc. CBPS. WebMed.https://www.medicines.org.